Hypoglycemic Activity of Hydro-Acetonic and HydroMethanolic Leaf and Bark Extracts of Bauhinia rufescens Lam in Mice

The purpose of this study was to determine the hypoglycaemic effects leaf and bark extracts Bauhinia rufescens Lam, used in traditional medicine for diabetes Senegal. Phytochemical screening hydromethanolic hydro-acetonic obtained from leaves barks carried out according standard analytical methods. Experiments were on normoglycemic diabetic mice. These after injection a single dose glucose (4 g/kg body weight). results showed that polyphenolic compounds, tannins, flavonoids main phytochemical constituents extracts. Then oral administration different Lam at doses 500, 700, 1000 mg/kg weight led significant reduction blood sugar (p < 0.05), similar antidiabetic action glibenclamide (10 Whatever organ extraction solvent, 500 700 induced dose-dependent hypoglycemia, just like glibenclamide. show metabolites revealed could be responsible their hypoglycemic effects. Thus, supported by complete chemical with view isolating active substances effect is possible. It will allowed formulate phytomedicine potential which makes possible uses populations treatment diabetes.